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sleep apnea
syndrome
Based on Introduction to
Polysomnography by S. Harding
and L. Shigley
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Polysomnography
• EOG - Electrooculogram
• EEG - Electroencephalogram
• EMG - Electromyogram
• EKG - Electrocardiogram
• Tracheal noise
• Nasal and oral airflow
• Thoracic and abdominal respiratory
effort
• Pulse oximetry
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Left EOG
Right EOG
Central
EEG
Occipital
EEG
Chin EMG
LEAD II
ECG
Left and
Right
Leg EMG
Tracheal
Noise
SAO2
Nasal and
oral Airflow
Thoracic
Respiratory
Effort
Left and Right
Electrooculogram
Left and Right
Electrooculogram
LOC
LOC
ROC
ROC
Eye
Blinks
Eye
Blinks
Electrooculography picks up
the inherent voltage of the
eye. The cornea has a
positive voltage output,
while the retina has a
negative polarity.
Electrooculography picks up
the inherent voltage of the
eye. The cornea has a
positive voltage output,
while the retina has a
negative polarity.
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C3
O1
Electroencephalogra
phy in the
Overnight Sleep
Study
G1
G2
Paper or computer screen
A2
Differential
Amplifier
C3-A2
O1-A2
G1
G1
G2
G2
Relaxed Jaw
Relaxed Jaw
Differential
Amplifier
G1
G1
G2
G2
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Open mouth or
Clenched Teeth
Open mouth or
Clenched Teeth
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Differential Amplifier
G1
G1
G2
G2
• Combination of
two dissimilar
metals
• Voltage changes
are seen with
exhalation and
inhalation
Thermocouple
Differential
Amplifier
Differential
Amplifier
Differential
Amplifier
Tracheal
Sound
Piezo Respiratory Effort
Anterior Tibialis
EMG
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Scoring Respiratory
Events
Basic Course
Obstructive Apnea
Central Apnea
Mixed Apnea
Hypopneas
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Common Rules
• All respiratory events need to be at
least 10 seconds long
• All events need to have at least a
3% SaO
2
desaturation
• EEG arousals will occur with most
respiratory events
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Obstructive Apnea
• No airflow for > 10 seconds
• Increasing respiratory effort.
Usually seen as paradoxical.
• SaO
2
desaturation <3% (may be
adjusted)
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Obstructive Apnea A complete blockage of the airway
despite efforts to breath. Notice the effort gradually
increasing ending in airway opening.
Blood oxygen levels
reduce to < 3% of
basline value
Inhal
e
Exhal
e
Airway obstructs
Airway
opens
Paradoxi
ng
Paradoxing
Ends
EKG
Airflow
Thoraci
c effort
Abd.
effort
SAO2
Effort gradually
increases
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• Hypopneas may be scored as
apnea when the SaO
2
<10% of
baseline level
• Same physiological consequence
as apnea
When Hypopneas are
Apnea
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Hypopnea This is an 18 second hypopneic event. The
airflow signal is reduced by approximately 50% during
this event.
Airflow reduction
SAO2 desaturation
> effort with paradox
Paradox ends
Inhale
Exhale
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Mixed Apnea
• A complete absence of nasal and
oral airflow
• A total absence of respiratory
effort at the beginning of the
event, followed by a gradual
increase in effort which
eventually breaks the apnea
• An oxygen desaturation of >3%
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Mixed Apnea
• May have a short central
component or a large one
• As with all events, mixed apneas
may be longer in REM
• May be created by
hyperventilation following an
obstructive apnea
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Mixed Apnea
EKG
Airflow
Thoracic Effort
Abdominal Effort
SAO2
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Central Apnea
• Absence of airflow at the nose and
mouth for > 10 seconds
• A complete absence of respiratory
effort as measured by:
– Thoracic Expansion
– Abdominal Expansion
– Intercostal / Diaphragmatic EMG
• SaO
2
drop of > 3%
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Central Apnea These are central apneas (2) with
minimal oxygen desaturation. Notice the low SAO2 at
the beginning of this tracing. This is associated with a
previous apnea.
Both of these events range between 13-16 seconds in
duration.
Airflo
w
Airflo
w
Thor.
Effor
t
Thor.
Effor
t
Abd.
Effor
t
Abd.
Effor
t
SAO
2
SAO
2
ECG
ECG
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OSA Treatment
• Obesity:
– Diet & behavior modification
– Bariatric surgery
• Positional Therapy:
– Raise the HOB
– Alarm
– Tee shirt (ball)
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OSA Treatment
• Increase muscle tone:
– Medications
– Electrical stimulation of the
genioglossus
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OSA Treatment
• Mechanically stent the upper airway:
– Nasal CPAP, BiPAP, Auto CPAP
– Oral devices
• Alter the upper airway:
– Soft tissue surgery
– Skeletal surgery
• Bypass the upper airway:
– Tracheostomy
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Positional Therapy: Raise HOB
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OSA Treatment
• Nasal CPAP is the treatment of choice
• Results in successful treatment in 95%
• Not as costly as surgery
• Long term compliance rates of 60-70%
• Improved long term survival (vs. UPPP)
• Can re-titrate the pressure if the
patient’s clinical condition changes
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Consequences of OSA
• Hypertension
• Heart infarction
• Stroke
• Heart arrhythmias
• Increased risk of traffic accidents
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Factors enhancing OSA
• Alcohol
• Drugs (morphine)
• Sedatives