OSA

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Sleep Academic Award

1

sleep apnea

syndrome

Based on Introduction to

Polysomnography by S. Harding
and L. Shigley

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Sleep Academic Award

2

Polysomnography

• EOG - Electrooculogram
• EEG - Electroencephalogram
• EMG - Electromyogram
• EKG - Electrocardiogram
• Tracheal noise
• Nasal and oral airflow
• Thoracic and abdominal respiratory

effort

• Pulse oximetry

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Sleep Academic Award

3

Left EOG

Right EOG

Central
EEG

Occipital
EEG
Chin EMG

LEAD II
ECG
Left and
Right
Leg EMG

Tracheal
Noise
SAO2

Nasal and
oral Airflow

Thoracic
Respiratory
Effort

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Left and Right

Electrooculogram

Left and Right

Electrooculogram

LOC

LOC

ROC

ROC

Eye
Blinks

Eye
Blinks

Electrooculography picks up

the inherent voltage of the

eye. The cornea has a

positive voltage output,

while the retina has a

negative polarity.

Electrooculography picks up

the inherent voltage of the

eye. The cornea has a

positive voltage output,

while the retina has a

negative polarity.

Sleep Academic Award

4

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Sleep Academic Award

5

C3

O1

Electroencephalogra
phy in the

Overnight Sleep

Study

G1

G2

Paper or computer screen

A2

Differential

Amplifier

C3-A2

O1-A2

G1

G1

G2

G2

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Relaxed Jaw

Relaxed Jaw

Differential

Amplifier

G1

G1

G2

G2

Sleep Academic Award 6

Open mouth or

Clenched Teeth

Open mouth or

Clenched Teeth

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Sleep Academic Award

7

Differential Amplifier

G1

G1

G2

G2

• Combination of

two dissimilar
metals

• Voltage changes

are seen with
exhalation and
inhalation

Thermocouple

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Differential

Amplifier

Differential

Amplifier

Differential

Amplifier

Tracheal
Sound

Piezo Respiratory Effort

Anterior Tibialis
EMG

Sleep Academic Award 8

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Sleep Academic Award

9

Scoring Respiratory

Events

Basic Course

Obstructive Apnea

Central Apnea

Mixed Apnea

Hypopneas

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Sleep Academic Award

10

Common Rules

• All respiratory events need to be at

least 10 seconds long

• All events need to have at least a

3% SaO

2

desaturation

• EEG arousals will occur with most

respiratory events

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Sleep Academic Award

11

Obstructive Apnea

• No airflow for > 10 seconds

• Increasing respiratory effort.

Usually seen as paradoxical.

• SaO

2

desaturation <3% (may be

adjusted)

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Sleep Academic Award

12

Obstructive Apnea A complete blockage of the airway

despite efforts to breath. Notice the effort gradually

increasing ending in airway opening.

Blood oxygen levels
reduce to < 3% of
basline value

Inhal
e

Exhal
e

Airway obstructs

Airway
opens

Paradoxi

ng

Paradoxing

Ends

EKG

Airflow

Thoraci
c effort

Abd.
effort

SAO2

Effort gradually
increases

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Sleep Academic Award

13

• Hypopneas may be scored as

apnea when the SaO

2

<10% of

baseline level

• Same physiological consequence

as apnea

When Hypopneas are
Apnea

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Sleep Academic Award

14

Hypopnea This is an 18 second hypopneic event. The
airflow signal is reduced by approximately 50% during
this event.

Airflow reduction

SAO2 desaturation

> effort with paradox

Paradox ends

Inhale

Exhale

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Sleep Academic Award

15

Mixed Apnea

• A complete absence of nasal and

oral airflow

• A total absence of respiratory

effort at the beginning of the
event, followed by a gradual
increase in effort which
eventually breaks the apnea

• An oxygen desaturation of >3%

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Sleep Academic Award

16

Mixed Apnea

• May have a short central

component or a large one

• As with all events, mixed apneas

may be longer in REM

• May be created by

hyperventilation following an
obstructive apnea

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Sleep Academic Award

17

Mixed Apnea

EKG

Airflow

Thoracic Effort

Abdominal Effort

SAO2

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Sleep Academic Award

18

Central Apnea

• Absence of airflow at the nose and

mouth for > 10 seconds

• A complete absence of respiratory

effort as measured by:

– Thoracic Expansion

– Abdominal Expansion

– Intercostal / Diaphragmatic EMG

• SaO

2

drop of > 3%

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Sleep Academic Award

19

Central Apnea These are central apneas (2) with

minimal oxygen desaturation. Notice the low SAO2 at

the beginning of this tracing. This is associated with a

previous apnea.
Both of these events range between 13-16 seconds in
duration.

Airflo
w

Airflo
w

Thor.
Effor
t

Thor.
Effor
t

Abd.
Effor
t

Abd.
Effor
t

SAO

2

SAO

2

ECG

ECG

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Sleep Academic Award

20

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Sleep Academic Award

21

OSA Treatment

• Obesity:

– Diet & behavior modification
– Bariatric surgery

• Positional Therapy:

– Raise the HOB
– Alarm
– Tee shirt (ball)

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Sleep Academic Award

22

OSA Treatment

• Increase muscle tone:

– Medications
– Electrical stimulation of the

genioglossus

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Sleep Academic Award

23

OSA Treatment

• Mechanically stent the upper airway:

– Nasal CPAP, BiPAP, Auto CPAP
– Oral devices

• Alter the upper airway:

– Soft tissue surgery
– Skeletal surgery

• Bypass the upper airway:

– Tracheostomy

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Sleep Academic Award

24

Positional Therapy: Raise HOB

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Sleep Academic Award

25

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Sleep Academic Award

26

OSA Treatment

• Nasal CPAP is the treatment of choice
• Results in successful treatment in 95%
• Not as costly as surgery
• Long term compliance rates of 60-70%
• Improved long term survival (vs. UPPP)
• Can re-titrate the pressure if the

patient’s clinical condition changes

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Sleep Academic Award

27

Consequences of OSA

• Hypertension
• Heart infarction
• Stroke
• Heart arrhythmias
• Increased risk of traffic accidents

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Sleep Academic Award

28

Factors enhancing OSA

• Alcohol
• Drugs (morphine)
• Sedatives


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