reprod w5 2010

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NOT ALWAYS
HAPPY

Postpartum depressive
disorders

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Mental health aspects of women’s
reproductive health. A global
review of the literature (WHO,
2009)

„There is now a consistent
view that psychological
disturbance following childbirth
can be conceptualized as
fittingone of three distinct
conditions, of differing severity:
transient mood disturbance,
depression
and psychotic illness.” (p.15)

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Types of postpartum
depressive disorders

Postpartum blues

Postpartum

depression

Postpartum

psychosis

Not listed in DSM-IV

In ICD-10 – no

special category of

depression (only

episodes of

depression, but…

F53.0 - mild disorders

F53.1 severe

disorders

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Postpartum blues

2-4 days after delivery

Usually lasts up to 2 weeks

Even in 80-85% of new mothers

Non-Anglophone 13- 50%

France 42%

Jamaica 60%

Arab countries 24%

Symptoms:

Episodes of crying

Emotional lability

Disturbances in sleep and appetite

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Postpartum blues – causal
factors

Emotional problems and depression in
pregnancy

Depressive symptoms before pregnancy

Premenstrual syndrome

Depressive symptoms more often in
older and better educated women (only
in normal pregnancy)

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Negative mood across time
(Murray & Cooper, 1997)

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What is postpartum
depression?

...nonpsychotic
depressive episode
that begins in or
extends into the
postpartum period

Dysphoric mood

sleep, appetite or
psychomotor
disturbance

fatigue

excessive guilt,
suicidal thought

AT LEAST 1 WEEK

„In practice, it is common for any
episode of depression during this
period (1 year after childbirth) to
be regarded as linked to the birth
(Scottish Intercollegiate
Guidelines Network, 2002).” p. 17

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Prevalence (how often?)

Oxford, UK - 8,7%

Edinburgh, UK - 9,9%

Iowa, USA - 10,4%

In teenage mothers –
26-32% (Aiken, 2000)

Single, young vs.
older than 30 yrs

Comparisons with
nonchildbearing
women show similar
rates of depression
prevalence!

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Postpartum depression -
symptoms

Low mood

Anxiety, being affraid of harming a baby

Guilt feelings

Low evaluation of oneself as the mother

Fatigue, poor concentration

Disturbances in sleep and appetite

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Negative mood across time
EPDS scores > 13

,

(A.Mandy 1998)

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Timing of onset (when?)

Within 3 months after the delivery

Kumar & Robson (1984) - 3 times as
many new cases as within 6 or 12
months

Watson et al. (1984) - 2/3 of all new
cases diagnosed during 1 postnatal year

Cox (1993) - 50% in the first 5 weeks

O’Hara (1990) - 69% within 3 weeks

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Depression in pregnancy and 1st postartum

year (M. Eberhard-Gran et al., 2004 -

Norway)

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Mental health aspects of women’s
reproductive health. A global
review of the literature (WHO,
2009)

„Despite the impression of
well-being in pregnancy,
comparable rates of depressive
symptoms have been
found among pregnant and
non-pregnant women. Large
systematic studies have
shown that rates of depression
in late pregnancy are
as high or higher than rates
of postpartum depression
(Zuckerman et al., 1989;
Da Costa et al., 2000; Evans
et al., 2001; Josefsson et al.,2001)” . p. 12

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Duration of an episode

Watson et al. (1984)

1/4 subject

3 months+, 1/4

6

months+

Kumar & Robson (1984)

50% 6 months or more

Campbell et al. (1992)

15 weeks or more

Burt & Hendricks (2005) – 4-8 weeks

similar duration in mothers and others

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Postpartum depression - causal
factors

Background factors

rarely socioeconomic factors, but…

In some studies depression more oftern in less educated

women (Johnstone et al., 2001; Tammentie et al., 2002)

Single motherhood

Unplanned pregnancy (Beck, 2001)

Biological (Harris, 1989, O’Hara, 1991)

lower level of progesterone – inconclusive

In breast feeding mothers – depression when low level

In bottle feeding mothers – depression when high levels

lower level of estradiol

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Causal factors -2

Gynaecological / obstetric

more in women with premenstrual tension
(Dennerstein 1988)

delivery complication - less (Paykel et al.,1980;
Pitt, 1968)

forceps or caesarean section (CS) - more
depression (O’Hara et al., 1991)

more recent studies (Hiltunen et al., 2004) – no
links between CS and depression

When anesthetics were used in labour – less depression
in 1st postpartum week (effect not present in 4th month
follow-up)

abortion or miscarriage - no increased risk

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Causal factors - 3

Stressful life events

more stresses - more depression (Hopkins et

al.. 1987)

Poor marital relationships

in pregnancy, postpartum - Gotlib, 1991;

Whiffen, 1988; Rubertsson et al. 2005

Lack of social support

Cutrona, 1984, O’Hara, 1994, Sender, 1999;

Eberhard-Garn et al., 2004

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Causal factors - 4

Personal and family psychopatholgy

anxiety in pregnancy (Gotlib, 1991)

previous psychiatric disorders (Marks,
1992)

depressed mothers

Meta-analyses show little or no
association between family
psychopathology and postparum
depression (O’Hara & Swain, 1996)

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Causal factors - 5

Psychological constructs

attributional style (Atkinson & Rickel,
1984; Cutrona, 1983; O’Hara et al., 1991)

Low self-esteem (WHO, 2009)

Attributional style can predict the
depressive symptoms NOT the diagnosis
of depression

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Causal factors – 6 (Rubertsson
et al., 2005)

Swedish representative sample (N=3293),
tested in pregnancy (16 weeks) and 2
months postpartum

12,3% - high level of depressive symptoms
postpartum

In some women - depression only after delivery

In others - depression both in pregnancy and
postpartum

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Causal factors – 7 (Rubertsson
et al., 2005)

Depression before and after delivery in

women who were:

Not employed

Younger than 25 yrs

Without a partner

Low educated

In unplanned pregnancy

Not receiving support from a child’s father and

others

In poor health

Experiencing at least 2 stressful events in the

year before pregnancy

Taking antidepresants before

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Causal factors – 8 (Rubertsson
et al., 2005)

Depression after delivery when:

Almost the same characteristics, but the relevant

risk was smaller

Poor child’s health

Frequent crying

Poor weight gain

Two types of etiological factors:

Background and family factors (before &

after)

Child’s health/behaviour (after)

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Mental health aspects of women’s
reproductive health. A global
review of the literature (WHO,
2009)

The birth of a daughter was found
to contribute independently to
postpartum depression in women
in India and Pakistan (Patel,
Rodrigues & DeSouza, 2002;
Chandran et al., 2002; Rahman,
Iqbal & Harrington., 2003) p. 14

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Depression in men after the
birth of their offspring

Prevalence – 10 – 30% (Soliday et al.,

1999)

Portugal – 5% (WHO, 2009)

Australia – 2,8% (WHO, 2009)

Onset (Ballard et al., 1994)

6 weeks after the delivery

Intensity of symptoms might increase in

next 6 months

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Variables related to men’s depressed

mood after the birth of their offspring

(Bielawska-Batorowicz & Kossakowska-Petrycka,

2006)

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Depression in women and

difficulties in parental role at 1

year postpartum

(L. Seimyr et al., 2004.)

EPDS

2 mo

EPDS

1 year

Maternal role

1 year

Paternal role

1 year

0,46*

0,07

0,41
*

0,29*

0,1
5*

*p<0,0
5

0,42*

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Some consequences

Perception of a baby as more difficult
(Edhborg, 2000)

Increased risk of future depression
over 5-years period

Phillips & O’Hara (1991) - 80% (42%
controls)

Cooper & Murray (1995) - 60% (35%)

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Consequences (for mothers)

When postpartum episode is the first
depression then:

episode is of shorter duration

less likely nonpostpartum depression

more likely subsequent postpartum
episode

depression due to biological or
psychological elements of giving birth

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Consequences for children

Infants whose mothers were
depressed postpartum show lower
scores in standard cognitive tests

The effect not observed when children
were 4-5 years old

Stronger effects of maternal depression
in disadvantaged families and when
depression lasts longer

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Consequences for children -
2

When fathers are depressed

(Ramchandani et al., 2005)

In children:

Emotional and behavioural problems

Hyperactivity

The negative effects of parental

depression more often detected

in male infants

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Postpartum psychosis

Prevalance 0,1 – 0,2 %

Tanzania – 0,32% (infections after delivery?)

In first month after delivery

Duration – several weeks (months)

Symptoms

Disorientation, ilusion, delusions, rapid mood

changes, insomnia

Postpartum psychosis considered as the

first episode of bipolar affective disorders

(Burt & Hendricks, 2005)


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