reprod w5 2008

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NOT ALWAYS
HAPPY

Postpartum depressive
disorders

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Types of postpartum
depressive disorders

Postpartum blues

Postpartum
depression

Postpartum
psychosis

Not listed in DSM-
IV

In ICD-10

F53.0 - mild
disorders

F53.1 severe
disorders

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Postpartum blues

2-4 days after delivery

Usually lasts up to 2 weeks

Even in 80-85% of new mothers

Symptoms:

Episodes of crying

Emotional lability

Disturbances in sleep and appetite

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Postpartum blues – causal
factors

Emotional problems and depression in
pregnancy

Depressive symptoms before pregnancy

Premenstrual syndrome

Depressive symptoms more often in
older and better educated women (only
in normal pregnancy)

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Negative mood across time
(Murray & Cooper, 1997)

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What is postpartum
depression?

...nonpsychotic
depressive episode
that begins in or
extends into the
postpartum period

Dysphoric mood

sleep, appetite or
psychomotor
disturbance

fatigue

excessive guilt,
suicidal thought

AT LEAST 1 WEEK

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Prevalence (how often?)

Oxford, UK - 8,7%

Edinburgh, UK - 9,9%

Iowa, USA - 10,4%

In teenage mothers – 26-32% (Aiken,
2000)

Comparisons with nonchildbearing women
show similar rates of depression
prevalence!

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Postpartum depression -
symptoms

Low mood

Anxiety, being affraid of harming a baby

Guilt feelings

Low evaluation of oneself as the mother

Fatigue, poor concentration

Disturbances in sleep and appetite

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Negative mood across time
EPDS scores > 13

,

(A.Mandy 1998)

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Timing of onset (when?)

Within 3 months after the delivery

Kumar & Robson (1984) - 3 times as
many new cases as within 6 or 12
months

Watson et al. (1984) - 2/3 of all new
cases diagnosed during 1 postnatal year

Cox (1993) - 50% in the first 5 weeks

O’Hara (1990) - 69% within 3 weeks

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Depression in pregnancy and 1st postartum

year (M. Eberhard-Gran et al., 2004 -

Norway)

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Duration of an episode

Watson et al. (1984)

1/4 subject

3 months+, 1/4

6

months+

Kumar & Robson (1984)

50% 6 months or more

Campbell et al. (1992)

15 weeks or more

Burt & Hendricks (2005) – 4-8 weeks

similar duration in mothers and others

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Postpartum depression - causal
factors

Background factors

rarely socioeconomic factors, but…

In some studies depression more oftern in less educated

women (Johnstone et al., 2001; Tammentie et al., 2002)

Single motherhood

Unplanned pregnancy (Beck, 2001)

Biological (Harris, 1989, O’Hara, 1991)

lower level of progesterone – inconclusive

In breast feeding mothers – depression when low level

In bottle feeding mothers – depression when high levels

lower level of estradiol

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Causal factors -2

Gynaecological / obstetric

more in women with premenstrual tension
(Dennerstein 1988)

delivery complication - less (Paykel et al.,1980;
Pitt, 1968)

forceps or caesarean section (CS) - more
depression (O’Hara et al., 1991)

more recent studies (Hiltunen et al., 2004) – no
links between CS and depression

When anesthetics were used in labour – less depression
in 1st postpartum week (effect not present in 4th month
follow-up)

abortion or miscarriage - no increased risk

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Causal factors - 3

Stressful life events

more stresses - more depression (Hopkins et

al.. 1987)

Poor marital relationships

in pregnancy, postpartum - Gotlib, 1991;

Whiffen, 1988; Rubertsson et al. 2005

Lack of social support

Cutrona, 1984, O’Hara, 1994, Sender, 1999;

Eberhard-Garn et al., 2004

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Causal factors - 4

Personal and family psychopatholgy

anxiety in pregnancy (Gotlib, 1991)

previous psychiatric disorders (Marks,
1992)

depressed mothers

Meta-analyses show little or no
association between family
psychopathology and postparum
depression (O’Hara & Swain, 1996)

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Causal factors - 5

Psychological constructs

attributional style (Atkinson & Rickel,
1984; Cutrona, 1983; O’Hara et al.,
1991)

Attributional style can predict the
depressive symptoms NOT the diagnosis
of depression

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Causal factors – 6 (Rubertsson
et al., 2005)

Swedish representative sample (N=3293),
tested in pregnancy (16 weeks) and 2
months postpartum

12,3% - high level of depressive symptoms
postpartum

In some women - depression only after delivery

In others - depression both in pregnancy and
postpartum

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Causal factors – 7 (Rubertsson
et al., 2005)

Depression before and after delivery in

women who were:

Not employed

Younger than 25 yrs

Without a partner

Low educated

In unplanned pregnancy

Not receiving support from a child’s father and

others

In poor health

Experiencing at least 2 stressful events in the

year before pregnancy

Taking antidepresants before

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Causal factors – 8 (Rubertsson
et al., 2005)

Depression after delivery when:

Almost the same characteristics, but the relevant

risk was smaller

Poor child’s health

Frequent crying

Poor weight gain

Two types of etiological factors:

Background and family factors (before &

after)

Child’s health/behaviour (after)

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Depression in men after the
birth of their offspring

Prevalence – 10 – 30% (Soliday et al.,
1999)

Onset (Ballard et al., 1994)

6 weeks after the delivery

Intensity of symptoms might increase in
next 6 months

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Variables related to men’s depressed

mood after the birth of their offspring

(Bielawska-Batorowicz & Kossakowska-Petrycka,

2006)

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Depression in women and

difficulties in parental role at 1

year postpartum

(L. Seimyr et al., 2004.)

EPDS

2 mo

EPDS

1 year

Maternal role

1 year

Paternal role

1 year

0,46*

0,07

0,41
*

0,29*

0,1
5*

*p<0,0
5

0,42*

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Some consequences

Perception of a baby as more difficult
(Edhborg, 2000)

Increased risk of future depression
over 5-years period

Phillips & O’Hara (1991) - 80% (42%
controls)

Cooper & Murray (1995) - 60% (35%)

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Consequences (for mothers)

When postpartum episode is the first
depression then:

episode is of shorter duration

less likely nonpostpartum depression

more likely subsequent postpartum
episode

depression due to biological or
psychological elements of giving birth

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Consequences for children

Infants whose mothers were
depressed postpartum show lower
scores in standard cognitive tests

The effect not observed when children
were 4-5 years old

Stronger effects of maternal depression
in disadvantaged families and when
depression lasts longer

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Consequences for children -
2

When fathers are depressed

(Ramchandani et al., 2005)

In children:

Emotional and behavioural problems

Hyperactivity

The negative effects of parental

depression more often detected

in male infants

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Postpartum psychosis

Prevalance 0,1 – 0,2 %

In first month after delivery

Duration – several weeks (months)

Symptoms

Disorientation, ilusion, delusions, rapid

mood changes, insomnia

Postpartum psychosis considered as

the first episode of bipolar affective

disorders (Burt & Hendricks, 2005)


Document Outline


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