Name:……………………………………………….……………..……Group 1

27.03.2007

1.Treatment of Pasteurella multocida infections:

a) is not required

b) includes penicillin

c) includes tetracyclines

d) includes chinolones

2. A patient presented to the eye casualty with a painful eye. Coneal scrappino showed the Gram negative bacilli. What is the most common predisposing factor for this infection?

a) S. aureus

b) P. aeruginosa

c) H. influenzae typ b

d) N. gonorrhoeae

3. Sings of H.ducreyi (chancroid or soft charice) include:

a) vomiting

b) stiff neck

c) diarrhea

d) papule and friable ulcer

4. Acellular B.pertussis vaccine contains:

a) LPS

b) polysaccharide capsule

c) tracheal cytotoxin

d) FHA, pertactin, pertussis toxoid

5. Which of the following is a preferred third - generation cephalosporin with good activity against childhood meningitis?

a) Penicillin

b) Vancomycin

c) Ceftazidine

d) Cefotaxime

6. A hyperemic edema of the larynx and epiglottis that rapidly leads to respiratory obstruction in young children is most likely to be caused by which of the following organisms?

a) Haemophilus hemolyticus

b) H. influenzae

c) K. pneumoniae

d) Neisseria meningitides

7. Primary gonococcal disease:

a) never initiates in the pharynx or rectum

b) occur only as acute male or female urethritis

c) is usually treated with penicillin

d) results in acute inflammatory response characterized by polymorphonuclear leukocytes attracted to the primary site by LOS and host complements.

8. Endotoxic shock, linked to the presence of toxic LPS in the cell wall, most frequently is induced by:

a) E.coli

b) Klebsiella spp.

c) Enterococcus spp.

d) Proteus spp.

9. Which one of the following E. coli types is characterized by the presence of LT (heat-labile) and ST (heat-stable) enterotoxins.

a) Enteroinvasive E. coli (EIEC)

b) Enterotoxigenic E. coli (ETEC)

c) Enterohemorrhagic E. coli (EHEC)

d) Enteropathogenic E. coli (EPEC)

10. E. coli O157H7 is a newsworthy microorganism that has been isolated from foods, with increasing frequency. Its characteristic biology is best described by which of the following statements?

a) It produces protein toxin that cause severe spasmodic cough, usually in children

b) It produces a toxin that blocks protein synthesis in an infected cell

c) It secretes an exotoxin that has been called “verotoxin” and “Shiga-like toxin”

d) It secretes an erythrogenic toxin that causes the characteristic signs of scarlet fever

Name:………………………………………………..………..……Group 2

29.03.2007

1. H.influenzae capsule type b consists of:

a) lipopolysaccharides (LPS)

b) polyribose - ribitol phosphate (PRP)

c) outer membrane protein (OMP)

d) lipooligosaccharide (LOS)

2. Typical signs of bubonic plague include:

a) pneumonia

b) exanthema

c) hepatomegaly

d) lymphadenitis (buboes)

3. What is the treatment for pertussis?

a) Vancomycin

b) Penicillin

c) ceftazidine

d) Erythromycin

4. Clinical signs of brucellosis include:

a) undulant fever

b) papular eruption

c) throat pains

d) conjunctivitis

5. There are variety of unusual bacteria that infect humans. While rare disease caused by these microorganisms is serious and occasionally difficult to identify. Which of the following statements best characterizes Moraxella catarrhalis?

a) A gram-negative, pleomorhic rod that can cause endocarditis

b) A gram-negative rod, fusiform-shaped, that is associated with periodontal disease but may cause sepsis.

c) The causative agent of sinusitis, bronchitis, and pneumonia

d) The causative agent of rat-bite fever

6. The person who contracts gonorrhoea is most likely to have acquired it via which of the following.

a) gastrointestinal tract

b) genital tract

c) nasal tract

d) skin

7. How is pertussis prevented?

a) IPV vaccine

b) DTaP vaccine

c) H i b vaccine

d) Hep B vaccine

8. The Kauffmann - white's scheme includes classification of serotypes of:

a) Salmonella spp.

b) Shigella spp.

c) E. coli

d) Proteus spp.

9. Shigellosis is common in travelers to developing countries. Infection is commonly acquired through which of the following routes?

a) gastrointestinal tract

b) genital tract

c) skin

d) respiratory tract

10. Diarrhea in travelers is commonly cause by

a) Proteus vulgaris

b) Klebsiella pneumoniae

c) ETEC (enterotoxigenic E. coli)

d) EPEC (enteropathogenic E. coli)

Name:………………………………………..……Group 3

29.03.2007

1. Which of the following tests would be most useful to differentiate Shigella flexneri from Shigella boydii?

a) fermentation of lactose

b) motility

c) agglutination in specific antisera

d) production of H₂S

2. Etiologic agent of meningitis in infants and children aged 2 months to 5 years:

a) Haemophilus influenzae type b

b) Streptococcus pneumoniae

c) Neisseria meningitidis

d) All of the above

3. Development of plague epidemics is related to:

a) coagulase production by Y.pestis

b) production of fibrinolysin by Y.pestis

c) both of the above

d) none of the above

4. One can get infected with brucellosis due to consumption of:

a) boiled meat

b) raw milk

c) fruit

d) water

5. N. gonorrhoeae is fastidious pathogen found in sites often contaminated with normal flora. What is the best medium for isolation.

a) Loffler's medium

b) Sheep blood agar

c) Thayer-Martin agar

d) Thisulfate citrate bile salts sucrose medium

6. Which of the following bacteria induce lesions to ciliated epithelial cells:

a) H.influenzae

b) P.aeruginosa

c) B.pertussis

d) S.aureus

7. The virulence factors N.memingitidis responible for or thought to faciliate adherence to the nospharyngeal mucosa are:

a) fagella and spores

b) exotoxins and enterotoxins

c) pili and IgA 1 protease

d) outer membrane proteins (OMP)

8. A sputum sample was brought to the laboratory for analysis. Gram stain revealed the following: rare epithelial cells, 8 to 10 polymorphonuclear leukocytes per high-power field, and pleomorphic gram-negative rods. As a laboratory consultant, which of the following interpretations should you make?

a) The appearance of the sputum is suggestive of H. influenzae

b) The patient has pneumococcal pneumonia

c) The sputum specimen is too contaminated by saliva to be useful

d) There is no evidence of an inflammatory response

9. A 2-year-old infant is brought to the emergency room with hemolytic uremic syndrom (HUS) and thrombocytopenia. Which one of the following bacteria would most likely be isolated from a stool specimen?

a) Salmonella enteritidis

b) E. coli O₁₅₇ H₇

c) Shigella flexneri

d) Klebsiella pneumoniae

10. H.influenzae capsule type b consists of:

a) lipopolysaccharides (LPS)

b) polyribose - ribitol phosphate (PRP)

c) outer membrane protein (OMP)

d) lipooligosaccharide (LOS)

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