4

Ck-.ir.mte: II

RENAL PHYSIOLOCY

PRINCIPLE Or TUDUIAR RIAOSORrTION LIMITATION (Tmi USINC CLUCOSE AS 1XAMPLE

Bctow Tm

Conccntiation o i glucosc in plasma. and con$$quontly in filtrate, is l*ss than reabsorptwe rapadty of tubulc; it is fully reabsofbed and

Al Tm

C<;ncont'afi:>n of fllucoi;^ ir pl^ma, .ind consequpntly in fili aic. i5|U5t sufficient to ^turate rcabsorptrve Cdpatily ottulnjle

*

Abctvc Tm

Conc«Miłr*tinn of glireno in pfaśma and con&ecucntlY in rlltrate, excceds reab^rptive capacity of tubule; Slucosoappoars n urine

t

U-

m

Figurę 6.6 Renal Hasoi inc, of Glucosf--

.rjew is iltered a! ihe gtorrea lus and reabsorbed b/ ttie pro:<imal    cosi- h in ilic urine. Tlie«e(ore, lic renal dearanc-r <>f ^lucow

'oc. Normclly, no gltcose appears In ihe trlne because all of ihc    will iiioease as lit- plasma conccnira-ion of slgcose mcrcases

-»ed Rhiiosi- IS reabsDrted However, * ihe plasma ccncemraibn c:uC050 s mcreaspil ie.g., as tan occurIn diabetes mellitus). &lu-