netter170

Thyroid Gland: Hormone Action

ENDOCRINE PHYSIOLOCY

T4®

t co₃

f Ventilation

f Cardiac output

Whole Body Effects

f Renal function

J. Perkins

MS, MFA

Figurę 8.10 Thyroid Hormone Action

Thyroxine (T_Ą) is converted to triiodothyronme (T,) al target Iłssues. T, binds to a nuclear receptor, resulting in transcription of a host of cellular proteins and enzymes. The net effect is an increase in meta-bolic ratę and 0_;. consumption. These effects are associated with increased heart, lung, and kidney function. T, is also important for norma! growth and development.

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