CIMG1215

Nowe możliwości terapeutyczne

IMc<m	Thei^euOc arna	FOA apprwal
ftnaafpsso	PancrrałK orcryme rophcomont
(Cr«on. Zonpop)	(harapy	2009
(Fonemowi		2010
(PoKtzye)		2012
(UHnass)		2012
Aztroonam lysato for ntalabon	ki hal od antibtocic	2010
(Cayston) Iwcaftor (Kalydeco)	CFTR potsntiMor	2012

TaW* I GFTR*ba«sd tharapioa compłatad ar In piogi»M wftftin the Thampautica PgyelopmorK Notwortt___

ProportDn af patiem*

wMh cautnUw    Ih«p«łt

Cm mutation mutmion (%ł    _

C551D/othor

Non 05510

aaUng^odior

RlimMlw

F508deV

FSOBdoi

PTC/o*m

10

fcracator

Waeaftot

lumacaftor-t-

Mcdtof VX-*41 ♦ KraeaAor Atdhasn

FOA approaad. aga >6

Aga S-6 ptawnod Wan wm

Wiaaa N (pAwiary andgaw nagaino*

CF, cyatic fibro*«*; CFTR. CF iwnsmombcana oaadaataaea    PTC.

UMmiaation codon.

«T 4Ł\

W

i?

m*

Clata I

(nonsonsa rrartotions)

PTC SlippPNMn Wtfcwo, ■mlftglyoffcMflWl

Cla*s III (Q6A10, othors)

Cla»* IV (R117M)

	PolonlUkiro 1	P^olmkUifcari ]
	fhrMaftor)	Ov«Mhw)

CIA** II (FSOOdel)

Corrtctor* 1* fo(MilUtart| INhmnIIW. VK-«*11* N—

-j

'W .

1