Tumor-specific antibody |
Tumor-specific antibody conjugated to toxin |
Tumor-specific antibody conjugated to radioisotope |
*r* 4 |
^ 4 | |
\/ Antibodies bind to the tumor celi |
N/ Antibody-toxin conjugates bind to the tumor celi |
V Radioactive antibody binds to the tumor celi |
^\CD16 | ||
C ^ |
d C~r> A | |
r1 ^7 hr ^ hr | ||
\/ NK cells with Fc receptors (CD16) are activated to kill the tumor cells |
Conjugates are internalized, killing the celi |
\/ Radiation kills the tumor celi and neighboring tumor cells |
Figurę 14-17 Immunobiology, 6/c. (O Garland Science 200S)