KATALIZA ASYMETRYCZNA

UMCS - Studia Doktoranckie

XI - XII. 2008

KATALIZA

ORGANOKATALIZA

KATALIZA ASYMETRYCZNA

z udziałem metali przejściowych

The Nobel Prize in Chemistry

2001

"for their work on chirally catalysed hydrogenation reactions„
"for his work on chirally catalysed oxidationreactions"

William S. Knowles

Ryoji Noyori

K. Barry Sharpless

1/4 of the prize

1/4 of the prize

1/2 of the prize

USA

Japan

USA

St. Louis, MO, USA

Nagoya University

Nagoya, Japan

The Scripps Research Institute

La Jolla, CA, USA

b. 1917

b. 1938

b. 1941

Dr William S. Knowles

Prof. Ryoji Noyori

Prof. K. Barry Sharpless

Rh

Cl

PPh

3

PPh

3

Ph

3

P

Pd

o

PPh

3

PPh

3

Ph

3

P

PPh

3

Wilkinson

Malatesta

William S. Knowles

William S. Knowles

William S. Knowles

William S. Knowles

William S. Knowles

William S. Knowles

William S. Knowles

William S. Knowles

William S. Knowles

William S. Knowles

William S. Knowles

William S. Knowles

Qudrant rules

William S. Knowles

William S. Knowles

Ryoji Noyori

Ryoji Noyori

Ryoji Noyori

Ryoji Noyori

Ryoji Noyori

Ryoji Noyori

Ryoji Noyori

Ryoji Noyori

Ryoji Noyori

Ryoji Noyori

Ryoji Noyori

Ryoji Noyori

Ryoji Noyori

Ryoji Noyori

Ryoji Noyori

Ryoji Noyori

Ryoji Noyori

Ryoji Noyori

Ryoji Noyori

Ryoji Noyori

Ryoji Noyori

Ryoji Noyori

Ryoji Noyori

Ryoji Noyori

Ryoji Noyori

Ryoji Noyori

K. Barry Sharpless

Asymmetric epoxidation of allylic alcohols

K. Barry Sharpless

Asymmetric epoxidation of allylic alcohols

K. Barry Sharpless

Chirally predictive model

Asymmetric epoxidation of allylic alcohols

K. Barry Sharpless

Asymmetric dihydroxylation of olefins

AD

-mix

α

AD

-mix

β

K. Barry Sharpless

K. Barry Sharpless

Asymmetric dihydroxylation of squalene

K. Barry Sharpless

K. Barry Sharpless

K. Barry Sharpless