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UP MS General Medicine major - suhjects of the Pre-clinical module - Course descnpmms - m odemie year of2015/2016

OAP-GT1 Pharmacology 1
Course director:	Dr. Erika PINTER, professor Department of Pharmacology and Pharmacotherapy

3 credit ■ semester exam ■ Pre-clinical module • autumn semester • recommended semester: 5 Number of hours/semesier:    14 lectures + 0 practices + 28 seminars = total ol 42 hours

Course headcount limilalions (min.-mwc.):    5 -

Prereąuisites:    0AA-BK2 completed + OAA-EL2 completed + OAA-NEA completed

Topie

The generał aim of ihe subject is to provide the medical students with alt the basie information in pharmacology ncccssaty to understand tlie actions of drugs and the clinical pharmacotherapy and to pass tlie Foreign Medical Graduate Examination in Medical Sciences. Phannacology can be deflned as tlie study of the manner in which the function of living sy stems is affected by Chemical agenis. Therefore. tlie students should be familiar with the basie knowledge of the physiological. pathophysiological and biochemical background of the phannacological and therapeutic approaches. On tlie other liand. drug tlierapy is closely relaled to the clinical aspects of diseases.

The following topics will be deall with. Definitions, prescription writing. drug development. drug formulations. General aspects of mechanisms of drug actions: characterization of dnig-receptor interactions. mechanisms of drug antagonism. signal transduclion cl of drag receptors. General and quantitative aspects of pliannacokinetics: absorption. distribution and elimination of drugs. Pharmacology of the autonomie nervous system and the respirator}' system.

Condilions for acceptance of the semester Maximum of 25 % abscncc allowed Mid-term exams Making up for missed classes

Each missed seminar has to be madę up for with another group in the same week.

Reading materiał

Obligatory literaturę

-    Literaturę developed by the Department

Materials related to the topics discussed in lectures and seminars will be available on the CooSpace.

-    Notes

-    Recommended literaturę

Rang, Dale, Ritter, Moore: Phannacology, 8^lh edition. Elsevier Churchill Lńingstone, 2015

B. G. Katzung (ed.): Basic and Clinical Phannacology. 12^,h edition, Lange Medical Books, McGraw-Hill, 2012

Goodman &amp: Gilman s The Pliarmacological Basis of Therapeutics, 12^,h edition. McGraw-Hill, 2011

Lectures

1    Introduction to phannacolog}'

Santicsne Dr. Pinter Erika

2    Introduction to neuropharmacology Santicsne Dr. Pinter Erika

3    Cholinergic stimulants Santicsne Dr. Pinter Erika

4    Muscarinic receptor antagonists Santicsne Dr. Pinter Erika

5    Neuromuscular blocking agents Dr. Pethó Gabor

6    Agents acting on noradrenergic neurons Dr. Petho Gabor

7    Adrenergic agonists I Santicsne Dr. Pinter Erika

8    Adrenergic agonists II Santicsne Dr. Pinter Erika

9    Adrenergic antagonists Santicsne Dr. Pinter Erika

10    Local anesthetics Tamasikne Dr. Helyes Zsuzsanna

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