1. Caracterisation du potentiel oncolytique in vitro de mutants du virus de la stomatite
1.1 Article 2. « Mutations in the glycoprotein of vesicular stomatitis virus affect
cytopathogenicity : Potential for oncolytic virotherapy » (J Virol 2011; 85 : 6513-20)........69
2. Caracterisation du potentiel immunomodulatoire de mutants du virus de la stomatite
2.1 Article 3. « The strength of the T celi response against a surrogate tumor antigen induced by
oncolytic VSV therapy does not correlate with tumor control. »(Soumis & Molecular Therapy).................................................................................................................................102
3. Influence du systeme du complement dans le contróle tumoral..................................136
3.1 Article 4. « Transient complement inhibition promotes a tumor-specific immune response
through the implication of natural killer cells. » (Cancer Immunol Res. 2013; 10.1158/2326-6066.CIR-13-0173)................................................................................................................137
162
178
182
Discussion.
Conclusion
Rćfćrences